Research Formulation Reference

CJC-1295 / Ipamorelin Research Peptide Blend

The Vial Drop Labs CJC-1295 / Ipamorelin research blend is a co-lyophilised two-component preparation containing CJC-1295 without DAC and Ipamorelin at 5 mg each. This reference identifies both components chemically and explains how a two-analyte blend is documented.

For research use only. Not for human consumption.

Formulation composition

CJC-1295 (no DAC)5 mg
Tetrasubstituted analogue of human GHRH(1-29) amide; the non-DAC form, carrying no albumin-binding Drug Affinity Complex
Ipamorelin5 mg
Synthetic pentapeptide, Aib-His-D-2-Nal-D-Phe-Lys-NH2
Total peptide content10 mg
Per sealed vial, lyophilised

Chemical identity reference

Component 1
CJC-1295 (no DAC)
CJC-1295 no DAC synonyms
Modified GRF (1-29), mod GRF(1-29), CJC-1295 without DAC
CJC-1295 no DAC structure
Analogue of human GHRH(1-29) amide carrying four substitutions relative to the native sequenceThe substitutions are described in the literature as improving resistance to enzymatic degradation; the D-alanine at position 2 is the substitution most consistently reported
CJC-1295 (with DAC) — a different molecule
C165H269N47O46, ≈ 3647.2 g/mol (PubChem CID 91971820)Listed only to make the distinction explicit; the DAC-bearing molecule is NOT what this blend contains
Component 2
Ipamorelin
Ipamorelin synonyms
NNC 26-0161
Ipamorelin structure
Aib-His-D-2-Nal-D-Phe-Lys-NH2Contains 2-aminoisobutyric acid and D-amino acid residues, so standard one-letter notation does not apply
Ipamorelin molecular formula
C38H49N9O5
Ipamorelin average molecular weight
≈ 711.9 g/mol
Ipamorelin CAS number
170851-70-4
Research classification
Two-component synthetic research peptide formulation, supplied lyophilised
Vial Drop research format
CJC-1295 (no DAC) 5 mg / Ipamorelin 5 mg, 10 mg total, lyophilised

"No DAC" is a chemical distinction, not a grade

Two different molecules circulate under the CJC-1295 name. The original CJC-1295 carries a Drug Affinity Complex — a maleimide linker attached to a lysine side chain that allows covalent binding to albumin. CJC-1295 without DAC, also published as Modified GRF (1-29), is the 29-residue peptide alone, with no such linker.

They differ in composition and mass: the DAC-bearing molecule is recorded in PubChem with the formula C165H269N47O46 and an average mass of approximately 3647 g/mol, which the non-DAC peptide does not share. Documentation, chromatography and mass measurement for one are not interchangeable with the other.

The Vial Drop Labs blend contains the no-DAC form, and it is labelled and documented as CJC-1295 (no DAC) throughout. Where a supplier does not state which form a document describes, the document cannot be compared with one that does.

Ipamorelin: chemical identity

Ipamorelin is a synthetic pentapeptide, Aib-His-D-2-Nal-D-Phe-Lys-NH2, with the molecular formula C38H49N9O5 and an average molecular weight of approximately 711.9 g/mol (CAS 170851-70-4).

Its structure includes 2-aminoisobutyric acid and two D-configured residues. That matters analytically: D/L isomers are chemically identical by mass, so mass measurement alone cannot confirm stereochemistry. Chromatographic behaviour against a reference standard is the practical identity check for a sequence of this kind.

Documenting a two-component blend

A single purity number cannot describe a preparation containing two analytes. Third-party reports for this blend resolve the two peptides chromatographically and state an area-percent purity and a measured content for each component against its own 5 mg label claim.

Published reports for Vial Drop Labs material are listed in the Research Documentation portal and are tied to the specific lot they were issued for.

Reading the analytical documentation

A Certificate of Analysis links a submitted sample to the analytical work performed on it. Current Vial Drop Labs reports are produced by validated HPLC-DAD methodology and answer two separate questions — what the material is, and how much of it is present.

  • Identity — on current Vial Drop Labs reports, identity is reported as conforming on the basis of retention time and UV/DAD spectral comparison against a reference standard. Current reports do not include mass-spectrometry results.
  • Purity — HPLC separates the dissolved sample across a column; the target peak's share of total integrated peak area is reported as an area-percent purity figure.
  • Content — peptide and compound reports separately state the content per vial in mg against the stated label claim. Chromatographic purity and content per vial are two different measurements and should not be read as one.
  • Sample scope — the report identifiers and test date describe the randomized sample the laboratory received and the batch it was drawn from as supplied to the laboratory. Recording the certificate ID alongside your own experimental records keeps the analytical record resolvable.
  • Scope — a report describes only the specific sample submitted. Unless a report expressly states otherwise, it does not assess sterility, endotoxin, microbial content, heavy metals or residual solvents, and it is not a safety or fitness-for-use determination.

How Vial Drop publishes analytical documentation

Vial Drop Labs publishes independent analytical reports for tested research materials, with available reports accessible through the Research Documentation portal against the research material and the sample identified on each report. Each analytical report applies only to the sample submitted for analysis and should not be interpreted as testing of every vial or production unit.

Not every report is publicly listed. Where no report has been published for a material, the portal shows none rather than substituting another material's, strength's or batch's results. Documentation is never averaged, combined, or extrapolated between lots.

Current reports are issued by an independent third-party analytical laboratory using validated HPLC-DAD methodology. They report chromatographic purity as area %, content per vial against label claim, and identity as conforming by retention-time and UV/DAD comparison against a reference standard. Current reports do not include mass-spectrometry results.

Vial Drop Labs makes no representation that material is pharmaceutical grade, clinical grade, sterile, safe, or approved by any regulatory authority. Published documentation states exactly what was tested, by which method, and on which date — nothing further should be inferred from it.

Laboratory storage and handling

Material is supplied lyophilised in a sealed glass vial. General laboratory practice for lyophilised peptides applies: store sealed at -20 °C for long-term storage, protect from light, and minimise exposure to atmospheric moisture.

Allow a cold sealed vial to equilibrate to ambient temperature before opening so that atmospheric moisture does not condense onto the dry cake. Lyophilised peptide material is hygroscopic, and repeated warm/cold cycling of an opened vial is the most common cause of avoidable degradation in a laboratory setting.

Handle as an uncharacterised laboratory chemical using standard laboratory protective equipment and institutional handling procedures.

Research use only

This material is supplied strictly as a laboratory research chemical. It is not a drug, supplement, cosmetic, food or medical device, and it is not manufactured, labelled or sold for human or animal use of any kind.

Vial Drop Labs does not provide, and cannot provide, dosing, administration, preparation-for-use, therapeutic or clinical guidance. Published information is limited to chemical identity, laboratory handling and analytical documentation.

Research catalog access

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FOR RESEARCH USE ONLY. NOT FOR HUMAN CONSUMPTION.