Selank Research Peptide

Selank is a seven-residue synthetic peptide, TKPRPGP. Its first four residues are tuftsin — Thr-Lys-Pro-Arg — a naturally occurring tetrapeptide fragment derived from immunoglobulin G. The final three residues, Pro-Gly-Pro, are a synthetic extension.

The design logic parallels Semax: the same C-terminal Pro-Gly-Pro motif is appended to a short natural fragment, and it is reported to slow enzymatic degradation relative to the unmodified parent peptide. Selank and tuftsin are nonetheless separate chemical entities, and Selank carries its own CAS registry number, 129954-34-3.

The sequence is strongly basic — it contains both lysine and arginine — which influences chromatographic retention and ionisation, and distinguishes it clearly from Semax in a chromatogram.

Selank emerged from the same Russian institutional lineage as Semax, developed jointly by the Institute of Molecular Genetics of the Russian Academy of Sciences and the Institute of Pharmacology of the Russian Academy of Medical Sciences, from earlier tuftsin-family peptide research.

Published work includes behavioural and mechanistic studies in animal models, a small Russian comparative clinical study in anxiety-spectrum conditions involving 62 participants, and more recent in-vitro work examining effects on gene expression in cultured neuronal cell lines.

The same evidence-base caveats apply as for Semax, and they are substantial: clinical work is small in scale, not consistently blinded or placebo-controlled by contemporary standards, published predominantly in Russian venues, and largely unreplicated by independent groups. This page describes what has been studied, not what any material does in a person.

At approximately 752 g/mol, Selank is characterised the same way as the other peptides documented here: an HPLC-DAD run reporting the area-percent share of the principal component and its content against label claim, with identity reported as conforming against a reference standard.

Independent analytical documentation for Vial Drop Labs Selank 10 mg is available in the Research Documentation library. A separate report covers the Semax / Selank 10mg / 10mg blend, and each report applies only to the material and tested sample it was issued for.

Because the sequence carries multiple basic residues, it typically elutes differently from a neutral or acidic peptide of similar size — the practical reason Semax and Selank can be resolved and quantified individually within a combined preparation.

A Certificate of Analysis links a submitted sample to the analytical work performed on it. Current Vial Drop Labs reports are produced by validated HPLC-DAD methodology and answer two separate questions — what the material is, and how much of it is present.

Vial Drop Labs publishes independent analytical reports for tested research materials, with available reports accessible through the Research Documentation portal against the research material and the sample identified on each report. Each analytical report applies only to the sample submitted for analysis and should not be interpreted as testing of every vial or production unit.

Not every report is publicly listed. Where no report has been published for a material, the portal shows none rather than substituting another material's, strength's or batch's results. Documentation is never averaged, combined, or extrapolated between lots.

Current reports are issued by an independent third-party analytical laboratory using validated HPLC-DAD methodology. They report chromatographic purity as area %, content per vial against label claim, and identity as conforming by retention-time and UV/DAD comparison against a reference standard. Current reports do not include mass-spectrometry results.

Vial Drop Labs makes no representation that material is pharmaceutical grade, clinical grade, sterile, safe, or approved by any regulatory authority. Published documentation states exactly what was tested, by which method, and on which date — nothing further should be inferred from it.

Material is supplied lyophilised in a sealed glass vial. General laboratory practice for lyophilised peptides applies: store sealed at -20 °C for long-term storage, protect from light, and minimise exposure to atmospheric moisture.

Allow a cold sealed vial to equilibrate to ambient temperature before opening so that atmospheric moisture does not condense onto the dry cake. Lyophilised peptide material is hygroscopic, and repeated warm/cold cycling of an opened vial is the most common cause of avoidable degradation in a laboratory setting.

Handle as an uncharacterised laboratory chemical using standard laboratory protective equipment and institutional handling procedures.

This material is supplied strictly as a laboratory research chemical. It is not a drug, supplement, cosmetic, food or medical device, and it is not manufactured, labelled or sold for human or animal use of any kind.

Vial Drop Labs does not provide, and cannot provide, dosing, administration, preparation-for-use, therapeutic or clinical guidance. Published information is limited to chemical identity, laboratory handling and analytical documentation.