Research Formulation Reference
Semax / Selank Research Peptide Blend
The Vial Drop Labs Semax / Selank research blend is a co-lyophilised preparation containing 10 mg Semax and 10 mg Selank per sealed vial. This reference distinguishes the two peptides chemically and explains how a two-analyte formulation is documented.
For research use only. Not for human consumption.
Formulation composition
- Semax10 mg
- Synthetic heptapeptide MEHFPGP, ACTH(4-7) analogue with C-terminal Pro-Gly-Pro
- Selank10 mg
- Synthetic heptapeptide TKPRPGP, tuftsin analogue with C-terminal Pro-Gly-Pro
- Total peptide content20 mg
- Per sealed vial, lyophilised
Chemical identity reference
- Formulation name
- Semax / Selank blend
- Format
- Co-lyophilised two-component blend, Semax 10 mg / Selank 10 mg, sealed vial
- Semax sequence
- MEHFPGP (Met-Glu-His-Phe-Pro-Gly-Pro)
- Semax molecular formula
- C37H51N9O10S
- Semax average molecular weight
- ≈ 813.9 g/mol
- Semax CAS number
- 80714-61-0
- Selank sequence
- TKPRPGP (Thr-Lys-Pro-Arg-Pro-Gly-Pro)
- Selank molecular formula
- C33H57N11O9
- Selank average molecular weight
- ≈ 751.9 g/mol
- Selank CAS number
- 129954-34-3
- Analytical approach
- Per-component HPLC-DAD (area %), with identity reported as conforming by retention-time and UV/DAD comparison against a reference standard
Two compounds, one vial
This formulation is not a single chemical entity and is not a new compound. It is a defined mixture of two separately synthesised heptapeptides, combined at 10 mg each and freeze-dried together so that a laboratory examining both does not need to reconstitute two vials.
Semax and Selank retain their individual identities in the mixture. Each has its own sequence, molecular formula, mass and CAS registry number, and each is characterised separately.
What distinguishes the two components
Semax is MEHFPGP: an analogue of the ACTH(4-7) fragment, containing methionine and histidine, with an average mass near 814 g/mol.
Selank is TKPRPGP: an analogue of the immunoglobulin-derived tetrapeptide tuftsin, strongly basic through its lysine and arginine residues, with an average mass near 752 g/mol.
What they share is the C-terminal Pro-Gly-Pro motif, appended in both cases to a short natural fragment. What they do not share is the fragment itself, their parent molecules, their charge characteristics, or their research literature. The comparison article linked below sets this out in detail.
Documenting a two-component blend
A blend has no single meaningful purity figure. Third-party reports for this formulation resolve the two peptides chromatographically and report an area-percent purity and a measured content for each against its own 10 mg label claim.
The two components differ in charge characteristics and separate cleanly on a reversed-phase column, which is what allows each to be reported individually for purity and content. Published reports for Vial Drop Labs material are listed in the Research Documentation portal against the specific lot they were issued for.
Reading the analytical documentation
A Certificate of Analysis links a submitted sample to the analytical work performed on it. Current Vial Drop Labs reports are produced by validated HPLC-DAD methodology and answer two separate questions — what the material is, and how much of it is present.
- Identity — on current Vial Drop Labs reports, identity is reported as conforming on the basis of retention time and UV/DAD spectral comparison against a reference standard. Current reports do not include mass-spectrometry results.
- Purity — HPLC separates the dissolved sample across a column; the target peak's share of total integrated peak area is reported as an area-percent purity figure.
- Content — peptide and compound reports separately state the content per vial in mg against the stated label claim. Chromatographic purity and content per vial are two different measurements and should not be read as one.
- Sample scope — the report identifiers and test date describe the randomized sample the laboratory received and the batch it was drawn from as supplied to the laboratory. Recording the certificate ID alongside your own experimental records keeps the analytical record resolvable.
- Scope — a report describes only the specific sample submitted. Unless a report expressly states otherwise, it does not assess sterility, endotoxin, microbial content, heavy metals or residual solvents, and it is not a safety or fitness-for-use determination.
How Vial Drop publishes analytical documentation
Vial Drop Labs publishes independent analytical reports for tested research materials, with available reports accessible through the Research Documentation portal against the research material and the sample identified on each report. Each analytical report applies only to the sample submitted for analysis and should not be interpreted as testing of every vial or production unit.
Not every report is publicly listed. Where no report has been published for a material, the portal shows none rather than substituting another material's, strength's or batch's results. Documentation is never averaged, combined, or extrapolated between lots.
Current reports are issued by an independent third-party analytical laboratory using validated HPLC-DAD methodology. They report chromatographic purity as area %, content per vial against label claim, and identity as conforming by retention-time and UV/DAD comparison against a reference standard. Current reports do not include mass-spectrometry results.
Vial Drop Labs makes no representation that material is pharmaceutical grade, clinical grade, sterile, safe, or approved by any regulatory authority. Published documentation states exactly what was tested, by which method, and on which date — nothing further should be inferred from it.
Laboratory storage and handling
Material is supplied lyophilised in a sealed glass vial. General laboratory practice for lyophilised peptides applies: store sealed at -20 °C for long-term storage, protect from light, and minimise exposure to atmospheric moisture.
Allow a cold sealed vial to equilibrate to ambient temperature before opening so that atmospheric moisture does not condense onto the dry cake. Lyophilised peptide material is hygroscopic, and repeated warm/cold cycling of an opened vial is the most common cause of avoidable degradation in a laboratory setting.
Handle as an uncharacterised laboratory chemical using standard laboratory protective equipment and institutional handling procedures.
Research use only
This material is supplied strictly as a laboratory research chemical. It is not a drug, supplement, cosmetic, food or medical device, and it is not manufactured, labelled or sold for human or animal use of any kind.
Vial Drop Labs does not provide, and cannot provide, dosing, administration, preparation-for-use, therapeutic or clinical guidance. Published information is limited to chemical identity, laboratory handling and analytical documentation.
Research catalog access
Availability for research materials is shown to signed-in customers with a confirmed 21+ attestation.