Research Compound Reference
KPV Research Peptide
KPV is the tripeptide L-lysyl-L-prolyl-L-valine, corresponding to residues 11–13 of α-melanocyte-stimulating hormone. This reference covers the chemical identity of the Vial Drop Labs KPV 10 mg research material and how it is documented analytically.
For research use only. Not for human consumption.
Chemical identity reference
- Compound name
- KPV
- Common synonyms
- Lys-Pro-Val, L-lysyl-L-prolyl-L-valine, α-MSH(11-13), MSH (11-13)
- Peptide sequence
- KPV (Lys-Pro-Val)
- Residue count
- 3 amino acids
- Molecular formula
- C16H30N4O4
- Average molecular weight
- ≈ 342.43 g/mol
- CAS number
- 67727-97-3
- Structural relationship
- C-terminal tripeptide fragment of α-melanocyte-stimulating hormone (residues 11–13)It does not contain the His-Phe-Arg-Trp melanocortin core sequence found in full-length α-MSH
- Research classification
- Synthetic tripeptide fragment
- Vial Drop research format
- KPV 10 mg, lyophilised
Chemical identity
KPV is one of the smallest peptides in routine research supply: three residues, lysine–proline–valine, with a molecular weight of approximately 342 g/mol. It corresponds to the C-terminal segment of α-melanocyte-stimulating hormone, residues 11 through 13.
Its relationship to α-MSH is sequence-based only. KPV does not include the His-Phe-Arg-Trp region that defines melanocortin receptor recognition in the parent hormone, and the two are separate chemical entities with separate identifiers. Literature discussing α-MSH should not be read as characterising KPV.
The proline residue gives the tripeptide a constrained backbone and cis/trans amide behaviour that can produce characteristic chromatographic profiles — a normal feature of proline-containing sequences rather than an indication of impurity.
Analytical methodology
Small peptides are analytically distinctive. Short, low-mass sequences sit close to common non-peptide species, so identity is established by comparison against a reference standard rather than by size alone, while chromatography quantifies the target peak against everything else the column resolves.
Short, polar sequences also elute early on reversed-phase columns, which is a method-development consideration: a report should state the method used, not only the number it produced.
Independent analytical documentation for Vial Drop Labs KPV 10 mg is available in the Research Documentation library.
Reading the analytical documentation
A Certificate of Analysis links a submitted sample to the analytical work performed on it. Current Vial Drop Labs reports are produced by validated HPLC-DAD methodology and answer two separate questions — what the material is, and how much of it is present.
- Identity — on current Vial Drop Labs reports, identity is reported as conforming on the basis of retention time and UV/DAD spectral comparison against a reference standard. Current reports do not include mass-spectrometry results.
- Purity — HPLC separates the dissolved sample across a column; the target peak's share of total integrated peak area is reported as an area-percent purity figure.
- Content — peptide and compound reports separately state the content per vial in mg against the stated label claim. Chromatographic purity and content per vial are two different measurements and should not be read as one.
- Sample scope — the report identifiers and test date describe the randomized sample the laboratory received and the batch it was drawn from as supplied to the laboratory. Recording the certificate ID alongside your own experimental records keeps the analytical record resolvable.
- Scope — a report describes only the specific sample submitted. Unless a report expressly states otherwise, it does not assess sterility, endotoxin, microbial content, heavy metals or residual solvents, and it is not a safety or fitness-for-use determination.
How Vial Drop publishes analytical documentation
Vial Drop Labs publishes independent analytical reports for tested research materials, with available reports accessible through the Research Documentation portal against the research material and the sample identified on each report. Each analytical report applies only to the sample submitted for analysis and should not be interpreted as testing of every vial or production unit.
Not every report is publicly listed. Where no report has been published for a material, the portal shows none rather than substituting another material's, strength's or batch's results. Documentation is never averaged, combined, or extrapolated between lots.
Current reports are issued by an independent third-party analytical laboratory using validated HPLC-DAD methodology. They report chromatographic purity as area %, content per vial against label claim, and identity as conforming by retention-time and UV/DAD comparison against a reference standard. Current reports do not include mass-spectrometry results.
Vial Drop Labs makes no representation that material is pharmaceutical grade, clinical grade, sterile, safe, or approved by any regulatory authority. Published documentation states exactly what was tested, by which method, and on which date — nothing further should be inferred from it.
Laboratory storage and handling
Material is supplied lyophilised in a sealed glass vial. General laboratory practice for lyophilised peptides applies: store sealed at -20 °C for long-term storage, protect from light, and minimise exposure to atmospheric moisture.
Allow a cold sealed vial to equilibrate to ambient temperature before opening so that atmospheric moisture does not condense onto the dry cake. Lyophilised peptide material is hygroscopic, and repeated warm/cold cycling of an opened vial is the most common cause of avoidable degradation in a laboratory setting.
Handle as an uncharacterised laboratory chemical using standard laboratory protective equipment and institutional handling procedures.
Research use only
This material is supplied strictly as a laboratory research chemical. It is not a drug, supplement, cosmetic, food or medical device, and it is not manufactured, labelled or sold for human or animal use of any kind.
Vial Drop Labs does not provide, and cannot provide, dosing, administration, preparation-for-use, therapeutic or clinical guidance. Published information is limited to chemical identity, laboratory handling and analytical documentation.
Research catalog access
Availability for research materials is shown to signed-in customers with a confirmed 21+ attestation.